Question 1

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Accepted Answer

A) True 
 B)False

Question 2

Drug tolerance is when more drug is needed to get the same desired effect over time.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following is not considered a fundamental component of pharmacokinetics?

Accepted Answer

A)   Drug metabolism
B)   Down regulation of drug receptors
C)   Drug elimination
D)   Drug absorption
E)   Drug distributionF) A) and D)
G) B) and C)

Question 4

An ergogenic drug is one that does what?

Accepted Answer

A)   Improves exercise performance
B)   Increases the rate of elimination
C)   Causes performance to deteriorate
D)   Alters the rate of metabolism of other drugs
E)   Displaces drugs from non-specific binding sitesF) A) and D)
G) D) and E)

Question 5

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Accepted Answer

A)   An antagonist
B)   An agonist
C)   A competitive inhibitor
D)   A suicide substrate
E)   An allosteric effectorF) C) and D)
G) B) and C)

Question 6

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Accepted Answer

A)   They are called a withdrawal syndrome.
B)   They are due to the ergogenic nature of the drug.
C)   They are determined from dose-response curves.
D)   They are based mostly on the pharmacokinetic properties of the drug.
E)   They are dependent of the liver status of the individual.F) None of the above
G) All of the above

Question 7

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

Accepted Answer

A)   Decreased due to the weight of the individual
B)   Increased due to a slow rate of absorption
C)   Decreased due to lower amounts bound to serum proteins
D)   Increased due to an increase in the volume of distribution
E)   Decreased due to added stress on the kidneysF) B) and E)
G) C) and D)

Question 8

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Accepted Answer

A) True 
 B)False

Question 9

A dose-response curve is useful in determining which of the following?

Accepted Answer

A)   Rates of drug elimination
B)   The drug's volume of distribution
C)   The number of genes involved in that drugs metabolism
D)   A drug's potency
E)   The best route of administrationF) C) and D)
G) A) and E) D

Question 10

How is the therapeutic index (TI)  used?

Accepted Answer

A)   To determine if a drug is ergolytic
B)   To determine the relative safety of a drug
C)   To determine the potency of a drug
D)   To determine the efficacy of a drug
E)   To determine the rate that a drug is metabolizedF) A) and C)
G) B) and E) B

Question 11

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Accepted Answer

A)   Serum proteins bind drugs tighter - with higher affinity
B)   Drugs are taken up faster in the stomach
C)   Blood flow decreases to the liver and kidneys
D)   Metabolism in muscle tissue increases significantly
E)   The rate of sweat formation increases significantlyF) B) and D)
G) A) and E)

Question 12

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

Accepted Answer

A) True 
 B)False

Question 13

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

Accepted Answer

A) True 
 B)False  True

Question 14

Intense exercise rarely alters a drug's bioavailability.

Accepted Answer

A) True 
 B)False

Question 15

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Accepted Answer

A) True 
 B)False

Exam 1: Basic Pharmacology

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Correct Answer
verified

Drug tolerance is when more drug is needed to get the same desired effect over time.

Correct Answer
verified

Which of the following is not considered a fundamental component of pharmacokinetics?

Correct Answer
verified

An ergogenic drug is one that does what?

Correct Answer
verified

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Correct Answer
verified

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Correct Answer
verified

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

Correct Answer
verified

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Correct Answer
verified

A dose-response curve is useful in determining which of the following?

Correct Answer
verified
D

How is the therapeutic index (TI) used?

Correct Answer
verified
B

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Correct Answer
verified

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

Correct Answer
verified

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

Correct Answer
verified
True

Intense exercise rarely alters a drug's bioavailability.

Correct Answer
verified

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Correct Answer
verified

Exam 1: Basic Pharmacology

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Correct AnswerverifiedShow Answer

Drug tolerance is when more drug is needed to get the same desired effect over time.

Correct AnswerverifiedShow Answer

Which of the following is not considered a fundamental component of pharmacokinetics?

Correct AnswerverifiedShow Answer

An ergogenic drug is one that does what?

Correct AnswerverifiedShow Answer

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Correct AnswerverifiedShow Answer

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Correct AnswerverifiedShow Answer

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

Correct AnswerverifiedShow Answer

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Correct AnswerverifiedShow Answer

A dose-response curve is useful in determining which of the following?

Correct AnswerverifiedD

How is the therapeutic index (TI) used?

Correct AnswerverifiedB

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Correct AnswerverifiedShow Answer

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

Correct AnswerverifiedShow Answer

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

Correct AnswerverifiedTrue

Intense exercise rarely alters a drug's bioavailability.

Correct AnswerverifiedShow Answer

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
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Correct Answer
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Correct Answer
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D

Correct Answer
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B

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True

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Correct Answer
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